Feasibility and utility of a flexible outcome assessment battery for longitudinal traumatic brain injury research: A TRACK-TBI
Bodien YG, Barber J, Taylor SR, Boase KD, Corrigan JD, Dikmen S, Gardner RC, Kramer J, Levin H, Machamer J, McAllister T, Nelson LD, Ngwenya LB, Sherer M, Stein MB, Vassar MJ, Whyte J, Yue JK, Markowitz AJ, McCrea M, Manley GT, Temkin N, Giacino J. J Neurotrauma. 2022 Sep 13. Epub ahead of print. <<PubMed>>
Outcomes in Patients With Mild Traumatic Brain Injury Without Acute Intracranial Traumatic Injury
Madhok DY, Rodriguez RM, Barber J, Temkin NR, Markowitz AJ, Kreitzer N, Manley GT, and the TRACK-TBI Investigators. JAMA Netw Open. 2022 Aug 1;5(8). <<PubMed>>
Diffusion Tensor Imaging Reveals Elevated Diffusivity of White Matter Microstructure that Is Independently Associated with Long-Term Outcome after Mild Traumatic Brain Injury: A TRACK-TBI Study
Palacios EM, Yuh EL, Mac Donald CL, Vassar MJ, Diaz-Arrastia R, Giacino JT, Okonkwo DO, Robertson CS, Stein MB, Temkin N, McCrea MA, Levin HS, Markowitz AJ, Jain S, Manley GT, Mukherjee P; TRACK-TBI Investigators. J Neurotrauma. 2022 Jul 18. doi: 10.1089/neu.2021.0408. Online ahead of print. <<PubMed>>
Prognostic Value of Day-of-Injury Plasma GFAP and UCH-L1 levels for Predicting Functional Recovery in the TRACK-TBI Cohort: an Observational Cohort Study
Korley F, Jain S, Sun X, Puccio A, Yue JK, Gardner RC, Wang KKW, Okonkwo DO, Yuh E, Mukherjee P, Nelson L, Taylor SR, Markowitz AJ, Diaz-Arrastia R, Manley GT and the TRACK-TBI Investigators. The Lancet Neurology. 2022 Sep;21(9):803-813. <<PubMed>>
Employment and Economic Outcomes of Mild Traumatic Brain Injury Participants in the TRACK-TBI Study
Gaudette E, Seabury S, Temkin N, Barber J, DiGiorgio A, Markowitz AJ, Manley GT and the TRACK-TBI Investigators. JAMA Network Open. 2022 June 1. <<PubMed>>
Association of Day-of-Injury Serum Glial Fibrillary Acidic Protein Concentration and Six-Month Posttraumatic Stress Disorder in Patients with Mild Traumatic Brain Injury
Kulbe JR, Jain S, Nelson LD, Korley FK, Mukherjee P, Sun X, Okonkwo DO, Giacino JT, Vassar M, Robertson C, McCrea MA, Wang KKW, Temkin N, Mac Donald C, Taylor S, Ferguson AR, Markowitz AJ, Diaz-Arrastia R, Manley GT, Stein MB, and the TRACK-TBI Investigators. Neuropsychopharmacology. 2022 June 18. <<PubMed>>
The Case for Optimized Edge-Centric Tractography at Scale
Moon J, Mukherjee P, Madduri R, Markowitz AJ, Palacios EM, and Manley GT. Frontiers in Neuroinformatics. 16 May 2022. <<PubMed>>
Incidence and Clinical Impact of Myocardial Injury Following Traumatic Brain Injury: A Pilot TRACK-TBI Study
Krishnamoorthy V, Manley GT, Jain S, Sun S, Foreman B, Komisarow, Laskowitz DT, Mathew JP, Hernandez A, James ML, Vavilala MS, MD, Markowitz AJ, Korley FK, and the TRACK-TBI Investigators. J Neurosurg Anesthesiol. 2022 Apr 1;34(2):233-237. <<PubMed>>
Trajectories of insomnia in adults after traumatic brain injury
Wickwire EM, Albrecht JS, Capaldi VF, Jain SO, Gardner RC, Werner JK, Mukherjee P, McKeon AB, Smith MT, Giacino JT, Nelson LD, Williams SG, Collen J, Sun X, Schnyer DM, Markowitz AM, Manley GT, & Krystal AD. JAMA Network Open. 2022 Jan 4;5(1):e2145310 <<PubMed>>
Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation
Galimberti S, Graziano F, Maas A, Isernia G, Lecky F, Jain S, Sun X, Gardner R, Taylor SR, Markowitz AJ, Manley GT, Valsecchi G, Bellelli G, Citerio G and CENTER-TBI & TRACK-TBI Investigators. The Lancet Neurology. 2022 Feb;21(2):153-162. <<PubMed>>
Mixture Model Framework for Traumatic Brain Injury Prognosis Using Heterogeneous Clinical and Outcome Data.
Kaplan AD, Cheng Q, Mohan KA, Nelson LD, Jain S, Levin H, Torres-Espin A, Chou A, Huie JR, Ferguson AR, Mccrea M, Giacino J, Sundaram S, Markowitz AJ, Manley GT. IEEE J Biomed Health Inform. 2022 Mar;26(3):1285-1296. <<PubMed>>
Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research
Kreitzer N, Jain S , Young JS, Sun X, Stein MB, McCrea M, Levin HS, Giacino J, Markowitz AJ, Manley GT, Nelson LD, and the TRACK-TBI Investigators. J Neurotrauma. 2021 Dec;38(23):3352-3363. doi: 10.1089/neu.2020.7546. Epub 2021 Oct 18.
Blood-based traumatic brain injury biomarkers - Clinical utilities and regulatory pathways in the United States Europe and Canada
Wang KK, Munoz Pareja JC, 3, Mondello S, Diaz-Arrastia R, 5 , Wellington C, 6, Kenney K, Puccio AM, Hutchison J, McKinnon N, Okonkwo DO, Yang Z, Kobeissy F, Tyndall JA, Büki A, Czeite E , Pareja Zabala MC, Gandham N, Berman R, and the InTBIR Biospecimens/Biomarkers Working Group. Expert Rev Mol Diagn. 2021 Dec;21(12):1303-1321. <<PubMed>>
Relationship Between Transdiagnostic Dimensions of Psychopathology and Traumatic Brain Injury (TBI): A TRACK-TBI Study
Nelson LD, Kramer MD, Joyner KJ, Patrick CJ, Stein MB, Temkin N, Levin HS, Whyte J, Markowitz AJ, Giacino JT, Manley GT and the TRACK-TBI Investigators. J Abnorm Psychol. 2021 Jul;130(5):423-434. <<PubMed>>
Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score
Bodien YG, Barra A, Temkin NR, Barber J, Foreman B, Vasser M, Robertson C, Taylor SR, Markowitz AJ, Manley GT, Giacino JT, Edlow BL, and the TRACK-TBI Investigators. J Neurotrauma. 2021 Dec;38(23):3295-3305. <<PubMed>>
Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury
Burke J, Gugger J, Ding K, Kim JA, Foreman B, Yue JK, Puccio AM, Yuh EL, MD, Sun X, Rabinowitz M, Vassar M, Taylor SR, Winkler EA, MD, Deng H, McCrea M, Stein MB, MD, Robertson CS, Levin HS, Dikmen S, Temkin NR, Barber J, Giacino JT, Mukherjee P, Wang KK, Okonkwo DO, Markowitz AJ, Jain SJ, Lowenstein D, Manley GT, Diaz-Arrastia, and the TRACK-TBI Investigators. JAMA Netw Open. 2021;4(12):e2140191. doi:10.1001/jamanetworkopen.2021.40191 <<Link>>
Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study
Williams JR, Nieblas-Bedolla E, Feroze A, Young C , Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL, and TRACK-TBI Investigators. Neurocrit Care. 2021 Jul 26. Online ahead of print. <<PubMed>>
Association of Vasopressor Choice with Clinical and Functional Outcomes Following Moderate to Severe Traumatic Brain Injury: A TRACK-TBI Study.
Toro C, Temkin N, Barber J, Manley G, Jain S, Ohnuma T, Komisarow J, Foreman B, Korley FK, Vavilala MS, Laskowitz DT, Mathew JP, Hernandez A, Sampson J, James ML, Goldstein BA, Markowitz AJ, Krishnamoorthy V and the TRACK-TBI Investigators. Neurocrit Care. 2021 Aug 2. Online ahead of print. <<PubMed>>
Pathological Computed Tomography Features Associated with Incomplete Recovery and Unfavorable Outcome After Mild Traumatic Brain Injury: A TRACK-TBI Study
Yuh EL, Jain S, Sun X, Pisica D, Harris M, Taylor SR, Markowitz AJ, Mukherjee P, Verheyden J, Giacino JT, Levin HS, McCrea M, Stein MB, Temkin NR, Diaz-Arrastia R, Robertson CS, Lingsma, Okonkwo DO, Maas A, Manley GT and The TRACK-TBI and CENTER-TBI Investigators. JAMA Neurol. doi:10.1001/jamaneurol.2021.2120. 19 July 2021. Online ahead of print.
Functional Outcome Over the First Year after Moderate-to-Severe Traumatic Brain Injury: A Prospective, Longitudinal TRACK-TBI Study
McCrea MA, Giacino JT, Barber J. Temkin NR, Nelson LD, Levin HS, Dikmen S, Stein M, Bodien YG, Boase K, Taylor SR, Vassar M, Mukherjee P, Robertson CS, Diaz-Arrastia R, Okonkwo DO, Markowitz AJ, Manley GT and the TRACK-TBI Investigators. JAMA Neurol. 2021 Jul 6. doi: 10.1001/jamaneurol.2021.2043. Online ahead of print.
Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury Findings From the TRACK-TBI Study
Brett BL, Kramer MD, Whyte J, McCrea MA, Stein MB, Giacino JT, Sherer M, Markowitz AJ, Manley GT, Nelson, LD Ph; and the TRACK-TBI Investigators. JAMA Netw Open. 2021;4(3):e213467.
Central curation of Glasgow Outcome Scale- Extended (GOSE) data: lessons learned from TRACK-TBI
Boase K, Machamer J, Temkin NR, Dikmen S, Wilson L, Nelson LD, Barber J, Bodien YG, Giacino JT, Markowitz AJ, McCrea M, Satris G, Stein MB, Taylor SR, Manley GT. J Neurotrauma. 2021 Apr 28. doi: 10.1089/neu.2020.7528. Online ahead of print.
A Manual for the Glasgow Outcome Scale-Extended (GOSE) Interview.
Wilson L, Boase K, Nelson LD, Temkin NR, Giacino JT, Markowitz AJ, Maas A, Menon DK, Teasdale G, Manley GT. J Neurotrauma. 2021 Apr 6. doi: 10.1089/neu.2020.7527. Online ahead of print.
Discrepancies in national databases for TBI estimates
Madhok DY, Hsia RY, Manley GT. Journal of Neurosurgery Letter to the Editor. Published online March 19, 2021; DOI: 10.3171/2020.12.JNS204327.
Relationship between transdiagnostic dimensions of psychopathology and traumatic brain injury (TBI): A TRACK-TBI study
Nelson LD, Kramer MD, Joyner KJ, Patrick CJ, Stein MB, Temkin N, Levin HS, Whyte J, Markowitz AJ, Giacino J, Manley GT and the TRACK-TBI Investigators. Journal of Abnormal Psychology. Advance online publication. doi: 10.1037/abn0000672
Smaller regional brain volumes predict posttraumatic stress disorder at 3 months after mild traumatic brain injury
Stein MB, Yuh E, Jain S, Okonkwo DO, MacDonald CL, Levin H, Giacino JT, Robertson CS, Nelson LD, McCrea MA, Sun X, Temkin N, Taylor SR, Markowitz AJ, Manley GT, Mukherjee P and the TRACK-TBI Investigators. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 6, 352-359. doi: 10.1016/j.bpsc.2020.10.008
A Comparison of GFAP and UCH-L1 Measurements from Two Prototype Assays: The Abbott i-STAT™ Alinity™ and ARCHITECT® Assays
Korley F, Datwyler SA, Jain S, Sun X, Beligere G, Chandran R, Marino J, McQuiston B, Zhang H, Caudle KL, Wang K, Puccio AM, Okonkwo DO, Yue JK, Taylor SR, Manley GT, Diaz-Arrastia R. In Press. Neurotrauma Reports. February 2021
Association of Gender and Age with Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study
Levin HS, Temkin NR, Barber J Nelson LD, Robertson C, Brennan J, Stein MB, Yue JK, Giacino JT, McCrea M, Diaz-Arrastia R, Mukherjee P, Okonkwo DO, Boase K, Markowitz AJ, Bodien Y, Taylor SR, Vassar MJ, Manley GT and the TRACK-TBI Investigators. JAMA Netw Open. 2021;4(4):e213046. doi:10.1001/jamanetworkopen.2021.3046
High-sensitivity C-Reactive Protein is a Prognostic Biomarker of 6-month Disability After Traumatic Brain Injury: Results from the TRACK-TBI Study
Xu L, Yue JK, Korley FK, Puccio AM, Yuh EL, Sun X, Rabinowitz M, Vassar M, Taylor SR, Ethan A Winkler EA, Puffer R, Deng H, McCrea M, Stein MB, Robertson CS, Levin H, Dikmen S, Temkin N, Giacino JT, Mukherjee P, Wang KW, Okonkwo DO, Markowitz AJ, Jain S, Manley GT, Diaz-Arrastia R. J Neurotrauma. 2020 Nov 9. Online ahead of print. <<PubMed>>
Validity of the Brief Test of Adult Cognition by Telephone (BTACT) in Level 1 Trauma Center Patients 6 Months Post-Traumatic Brain Injury: A TRACK-TBI Study
Nelson LD, Barber J, Temkin N, Dams-O’Connor K, Dikmen S, Giacino JT, Kramer M, Levin HS, McCrea M, Whyte J, Bodien YG, Yue JK, Manley GT and the TRACK-TBI Investigators. J Neurotrauma. 2020 Oct 27. Online ahead of print. <<PubMed>>
An evidence-based methodology for systematic evaluation of clinical outcome assessment measures for traumatic brain injury
Christoforou A, Armstrong MBergin MJ, Robbins A, Merillat S, Erwin P, Getchius T, McCrea M, Markowitz A, Manley GT, Giacino JT. PLoS One. 2020 Dec 14;15(12):e0242811. <<PubMed>>
Point-of-Care Platform Blood Biomarker Testing of GFAP versus S100B for Prediction of Traumatic Brain Injuries: a TRACK-TBI study
Okonkwo DO, Puffer RC, Puccio AM, Yuh EL, Yue JK, Diaz-Arrastia R, Korley FK, Wang KW, Sun X, Sabrina Taylor SR, Mukherjee P, Markowitz AJ, Jain S, Manley GT and the TRACK-TBI Investigators. J Neurotrauma. 2020 Aug 28. Online ahead of print. <<PubMed>>
Risk Factors for Suicidal Ideation Following Mild Traumatic Brain Injury: A TRACK-TBI Study
Campbell-Sills L, Jain S, Sun X, Fisher LB, Agtarap SD, Dikmen S, Nelson LD, Temkin N, McCrea M, Yuh E, Giacino JT, Manley GT, Stein MB; TRACK-TBI Investigators. J Head Trauma Rehabil. 2020 Jul 22. Online ahead of print. <<PubMed>>
Polytrauma Is Associated with Increased Three- and Six-Month Disability after Traumatic Brain Injury: A TRACK-TBI Pilot Study
Yue JK, Satris GG, Dalle Ore CL, Huie JR, Deng H, Winkler EA, Lee YM, Vassar MJ, Taylor S, Schnyer DM, Lingsma HF, Puccio AM, Yuh EL, Mukherjee P, Valadka AB, Ferguson AR, Markowitz AJ, Okonkwo DO, Manley GT and the TRACK-TBI Investigators. Neurotrauma Reports. Vol. 1, No. 1. July 2020.
Satisfaction with Life Following Mild Traumatic Brain Injury: A TRACK-TBI Study
Agtarap, SD, Campbell-Sills, L, Jain, S, Sun, X, Dikmen, S, Levin, H, McCrea, MA, Mukherjee, P, Nelson, LD, Temkin, N, Yuh, E, Giacino, JT, Manley, GT, Stein, MB & the TRACK-TBI Investigators. J Neurotrauma. In Press.
The evolution of white matter changes after mild traumatic brain injury: A DTI and NODDI study.
Palacios EM, Owen J, Yuh EL, Wang M, Vassar MJ, Ferguson AR, Diaz-Arrastia R, Giacino J, Okonkwo DO, Robertson CS, Stein MB, Temkin NR, Jain S, McCrea M, Mac Donald C, Levin HS, Manley GT, Mukherjee P. Sci Adv. 2020 Aug 7;6(32 2020 Aug. <<PMID>>
Assessing physical function and mobility following pediatric traumatic brain injury with the NIH Toolbox Motor Battery: A feasibility study.
Evans E, Cook NE, Iverson G, Townsend EL, Duhaime, AC, and TRACK-TBI Investigators. Phys Occup Ther Pediatr. 2020 May 12;1-18. <<PubMed>>
Clinical Predictors of 3- and 6-Month Outcome for Mild Traumatic Brain Injury Patients with a Negative Head CT Scan in the Emergency Department: A TRACK-TBI Pilot Study.
Madhok DY, Yue JK, Sun X, Suen, Coss N, Jain S, Manley GT, and the TRACK-TBI Investigators. Brian Sciences. 1 May 2020. <<PubMed>>
Monitoring outcome after hosptial-presenting milder spectrum pediatric traumatic brain injury using the Glasgow Outcome Scale Extended, Pediatric Revision.
Evans E, Cook NE, Iverson G, Townsend EL, Duhaime, AC, and TRACK-TBI Investigators. Monitoring. J Neurotrauma. April 2020. Epub ahead of print. <<PubMed>>
Substance use on admission toxicology screen is associated with peri-injury factors and six-month outcome after traumatic brain injury: A TRACK-TBI Pilot study.
Yue JK, Phelps RRL, Winkler EA, Deng H, Upadhyayula PS, Vassar MJ, Madhok DY, Schnyer DM, Puccio AM, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. J Clin Neurosci. 2020 Mar 12. Epub ahead of print. PMID 32173156. <<PubMed>>
Biomarkers for traumatic brain injury: Data standards and statistical considerations.
Huie JR, Mondello S, Lindsell C, Antiga L, Yuh EL, Zanier ER, Masson S, Rosario B, Ferguson AR; TRACK-TBI Investigators. J Neurotrauma. 2020 Feb 11. Epub ahead of print. PMID 32046588. <<PubMed>>
Statistical guidelines for handling missing data in traumatic brain injury clinical research.
Nielson JL, Cooper SR, Seabury SA, Luciani D, Fabio A, Temkin NR, Ferguson AR; TRACK-TBI Investigators. J Neurotrauma. 2020 Mar 10. Epub ahead of print. PMID 32008424 <<PubMed>>
Unsupervised machine learning reveals novel traumatic brain injury patient phenotypes with distinct acute injury profiles and long-term outcomes.
Folweiler KA, Sandsmark DK, Diaz-Arrastia R, Cohen AS, Masino AJ. J Neurotrauma. 2020 Mar 11. Epub ahead of print. PMID 32008422<<PubMed>>
Common Data Elements: Critical Assessment of Harmonization between Current Multi-Center Traumatic Brain Injury Studies.
Meeuws S, Yue JK, Huijben JA, Nair N, Lingsma HF, Bell MJ, Manley GT, Maas AIR. J Neurotrauma. 2020 Feb 25. doi: 10.1089/neu.2019.6867. [Epub ahead of print]
Invariance of the bifactor structure of mild traumatic brain injury (mTBI) symptoms on the RPQ across time, demographic characteristics, and clinical groups: A TRACK-TBI study.
Agtarap S, Kramer MD, Campbell-Sills L, Yuh E, Mukherjee P, Manley GT, McCrea MA, Dikmen S, Giacino JT, Stein MB, Nelson LD, and the TRACK-TBI Investigators. (in press). Assessment. Advance online publication, doi: 10.1177/1073191120913941
Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study
Yue JK, Yuh EL, Korley FK, Winkler EA, Sun X, Puffer RC, Hansen D, Choy Wm, Taylor SR, Ferguson AR, Huie R, Rabinowitz M, Puccio AM, Mukherjee PM, Vassar MJ, Wang KKW, Diaz-Arrastia R, Okonkwo DO, Jain S, Manley GT, and the TRACK-TBI Investigators. The Lancet Neurology. In Press. Available online 23 August 2019.
Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge
in Traumatic Brain Injury (TRACK-TBI) Study
Nelson LD, Temkin NR, Dikmen D, Barber J, Giacino JT, Yuh E, Levin HS, McCrea MA, Stein MB, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT; and the TRACK-TBI Investigators. JAMA Neurol. 2019 June 3. Epub ahead of print. PMID 31157856. <<PubMed>>
Diagnosing the GOSE: Structural & psychometric properties using item response theory, A TRACK-TBI Pilot Study.
Ranson J, Magnus BE, Temkin N, Dikmen S, Giacino J, Okonkwo DO, Valadka A, Manley GT, Nelson LD; TRACK-TBI Investigators. J Neurotrauma. 2019 Mar 23. Epub ahead of print. PMID 30907261. <<PubMed>>
Functional status examination versus Glasgow Outcome Scale Extended as outcome measures in traumatic brain injuries: How do they compare?
Dikmen S, Machamer J, Manley GT, Yuh EL, Nelson LD, Temkin NR; TRACK-TBI Investigators. J Neurotrauma. 2019 Mar 2. Epub ahead of print. PMID 30827167. <<PubMed>>
Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study
Stein MB, Jain S, Giacino JT, Levin H, Dikmen S, Nelson L, Vassar MJ, Okonkwo DO, Diaz-Arrastia R, Robertson C, Mukherjee P, McCrea M, Mac Donald CL, Yue JK, Yuh E, Sun X, Campbell-Sills L, Temkin N, Manley GT, and the TRACK-TBI Investigators. JAMA Psychiatry. January 30, 2019. PMID: 30698636. <<PubMed>>
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The Temporal Relationship of Mental Health Problems and Functional Limitations following mTBI: A TRACK-TBI and TED Study
Zahniser E, Nelson LD, Dikmen S, Machamer J, Stein M, Yuh E, Manley GT, Temkin N, and the TRACK-TBI Investigators. J Neurotrauma. 2019 Jan 31. [Epub ahead of print] PMID: 30543138 <<PubMed>>
The Evolution of White Matter Changes After Mild Traumatic Brain Injury :A DTI and NODDI Study.
Palacios E, Owen J, Yuh E, Wang M, Vassar Mary, Ferguson A, Diaz-Arrastia R, Giacino J, Okonkwo D, Robertson C, Stein M, Temkin N, Jain S, McCrea M, Mac Donald C, Levin H, Manley G, Mukherjee P. Submitted to BRAIN. Preprint published on bioRxiv: https://doi.org/10.1101/345629
Assessment of Follow-up Care After Emergency Department Presentation for Mild Traumatic Brain Injury and ConcussionResults From the TRACK-TBI Study
Seabury S, Gaudette E, Goldman D, Markowitz A, Brooks J, McCrea M, Okonkwo D, Manley G, and the TRACK-TBI Investigators. JAMA Network Open. 2018 May 5. <<LINK>>
Age-related differences in diagnostic accuracy of plasma GFAP and Tau for identifying acute intracranial trauma on CT: A TRACK-TBI study.
Gardner RC, Rubenstein R*, Wang KKW, Korley FK, Yue JK, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2018 May 2. PMID 29717620. <<PubMed>>
Geriatric Traumatic Brain Injury: Epidemiology, Outcomes, Knowledge Gaps, and Future Directions
Gardner RC, Dams-O-Connor K, Morrissey MR, Manley GT. J Neurotrauma. Epub ahead of print. Feb 15, 2018. PMID: 29212411 <<PubMed>>
An update on diagnostic and prognostic biomarkers for traumatic brain injury.
Wang KK, Yang Z, Zhu T, Shi Y, Rubenstein R, Tyndall JA, Manley GT. Expert Rev Mol Diagn. 2018 Jan 23:1-16. <<PubMed>>
Comparing Plasma Phospho Tau, Total Tau, and Phospho Tau-Total Tau Ratio as Acute and Chronic Traumatic Brain Injury Biomarkers.
Rubenstein R, Chang B, Yue JK, Chiu A, Winkler EA, Puccio AM, Diaz-Arrastia R, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Davies P, Agarwal S, Lin F, Sarkis G, Yadikar H, Yang Z, Manley GT, Wang KKW; and the TRACK-TBI Investigators, Cooper SR, Dams-O'Connor K, Borrasso AJ, Inoue T, Maas AI, Menon DK, Schnyer DM, Vassar MJ. JAMA Neurol. 2017 Sep 1;74(9):1063-1072. PMID 28738126. <<PubMed>>
Resting-State Functional Connectivity Alterations Associated with Six-Month Outcomes in Mild Traumatic Brain Injury.
Palacios EM, Yuh EL, Chang Y, Yue JK, Schnyer DM, Okonkwo DO, Valadka AB, Gordon WA, Maas AIR, Vassar M, Manley GT, Mukherjee P. J Neurotrauma. 2017 April 15;34(8):1546-1557. <<PubMed>>
The Traumatic Brain Injury Endpoints Development (TED) Initiative: Progress on a Public-Private Regulatory Collaboration to Accelerate Diagnosis and Treatment of Traumatic Brain Injury.
Manley GT, MacDonald CL, Markowitz A, Stephenson D, Robbins A, Gardner RC, Winkler EA, Bodien Y, Taylor S, Yue JK, Kannan L, Kumar A, McCrea M, Wang KK,. J Neurotrauma. 2017 March 31. Epub ahead of print. PMID 28363253. <<PubMed>>
Mild Traumatic Brain Injury: Longitudinal Study of Cognition, Functional Status, and Post-Traumatic Symptoms.
Dikmen S, Machamer J, Temkin N. J Neurotrauma. 2016 Dec 2. Epub ahead of print. PMID 27785968. <<PubMed>>
Using Multivariate Base Rates to Interpret Low Scores on an Abbreviated Battery of the Delis-Kaplan Executive Function System.
Karr, JE., Iverson, GL, & Garcia-Barrera, MA. Archives of Clinical Neuropsychology. 2016 Dec 1. Epub ahead of print. PMID 27913387. <<PubMed>>
Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker
Zhihui Yang and Kevin K.W. Wang. Trends in Neuroscience 2015 June <<Link>>
Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury.
Yue JK, Pronger AM, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT; The COBRIT Investigators; The TRACK-TBI Investigators. Neurogenetics 2015 Jan 30. [Epub ahead of print] <<PubMed>>
C-51Differences in Neuropsychological Test Performance at 3 Months Post-Injury among CT Positive and CT Negative Mild TBI Patients.
Henry L, Pardini J, McMahon P, Nwachuku E, Okonkwo D. Arch Clin Neuropsychol 2014 Sep;29(6):592-3. <<PubMed>>
Measurement of the Glial Fibrillary Acidic Protein and Its Breakdown Products GFAP-BDP Biomarker for the Detection of Traumatic Brain Injury Compared to Computed Tomography and Magnetic Resonance Imaging.
McMahon PJ1, Panczykowski DM, Yue JK, Puccio AM, Inoue T, Sorani MD, Lingsma HF, Maas AI, Valadka AB, Yuh EL, Mukherjee P, Manley GT, Okonkwo DO, Casey SS, Cheong M, Cooper SR, Dams-O'Connor K, Gordon WA, Hricik AJ, Lawless K, Menon D, Schnyer DM, Vassar MJ. J Neurotrauma. 2014 Sep 29. <<PubMed>>
Outcome Prediction After Mild and Complicated Mild Traumatic Brain Injury: External Validation of Existing Models and Identification of New Predictors Using the TRACK-TBI Pilot Study.
Lingsma H, Yue JK, Maas A, Steyerberg EW, Manley GT, Cooper SR, Dams-O'Connor K, Menon D, Mukherjee P, Okonkwo DO, Puccio AM, Schnyer DM, Valadka A, Vassar MJ, Yuh EL. J Neurotrauma 2014 Jul 15. <<PubMed>>
ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: analysis of the Transforming Research and Clinical Knowledge in TBI study.
Ratcliff JJ, Adeoye O, Lindsell CJ, Hart KW, Pancioli A, McMullan JT, Yue JK, Nishijima DK, Gordon WA, Valadka AB, Okonkwo DO, Lingsma HF, Maas AI, Manley GT; TRACK-TBI investigators. Am J Emerg Med 2014 Aug;32(8):844-50. <<PubMed>>
Diffusion tensor imaging for outcome prediction in mild traumatic brain injury: a TRACK-TBI study.
Yuh EL, Cooper SR, Mukherjee P, Yue JK, Lingsma HF, Gordon WA, Valadka AB, Okonkwo DO, Schnyer DM, Vassar MJ, Maas AI, Manley GT, Casey SS, Cheong M, Dams-O'Connor K, Hricik AJ, Inoue T, Menon DK, Morabito DJ, Pacheco JL, Puccio AM, Sinha TK. J Neurotrauma 2014 Sep 1;31(17):1457-77. <<PubMed>>
Symptomatology and functional outcome in mild traumatic brain injury: results from the prospective TRACK-TBI study.
McMahon P, Hricik A, Yue JK, Puccio AM, Inoue T, Lingsma HF, Beers SR, Gordon WA, Valadka AB, Manley GT, Okonkwo DO; TRACK-TBI Investigators. J Neurotrauma 2014 Jan 1;31(1):26-33. <<PubMed>>
The impact of previous traumatic brain injury on health and functioning: a TRACK-TBI study.
Dams-O'Connor K, Spielman L, Singh A, Gordon WA, Lingsma HF, Maas AI, Manley GT, Mukherjee P, Okonkwo DO, Puccio AM, Schnyer DM, Valadka AB, Yue JK, Yuh EL; TRACK-TBI Investigators. J Neurotraum. 2013 Dec 15;30(24):2014-20. <<PubMed>>
Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein.
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